Purpose: The aim of the present study was to evaluate the feasibility of ARFI-measurements in combining of VTI and eSie Touch images in the thyroid nodule.
Methods and materials: All patients underwent conventional ultrasound, ARFI-imaging and cytological assessment. ARFI-imaging (VTI and VTQ technology) and eSie Touch technology were performed with 9L4 probe, using Siemens (ACUSON S2000) B-mode-ARFI combination transducer.
Results: 85 nodules were available for analysis. 67 nodules were benign on cytology, 13 nodules were malignant (13 papillary carcinomas), and 5 follicular lesions.
The median velocity of ARFI-imaging in benign and malignant thyroid nodules was of 2.06 m/s, and of 3.00 m/s, respectively. A specificity of ARFI-imaging of 95% could be achieved using a cut-off of 3.1 m/s (area under ROC curve is 0.778). We realized that should combine the ARFI velocity with VTI and eSie Touch images in the characterization of malignant nodules and follicular lesions which were in dark color from benign nodules, in bright color, because there was an overlapping of the ARFI velocity values between them.
Conclusions: ARFI can be performed in thyroid nodule with reliable results. ARFI might be the reference criteria for differentiation of benign and malignant thyroid nodules.